Recombinant Human / Mouse / Rat BMP-2

In stock

Catalog ID

800-02

Size	Stock	SKU	Unit Price
10 µg	In Stock	800-02-10UG	$183.00
100 µg	In Stock	800-02-100UG	$590.00
500 µg	In Stock	800-02-500UG	$2,774.00
1 mg	In Stock	800-02-1MG	$4,623.00
10 µg (Animal-Free)	In Stock	800-02AF-10UG	$200.00
100 µg (Animal-Free)	In Stock	800-02AF-100UG	$651.00
500 µg (Animal-Free)	Inquire for Availability	800-02AF-500UG	$3,053.00
1 mg (Animal-Free)	Inquire for Availability	800-02AF-1MG	$5,086.00

Find Your Distributor

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Details

Bone morphogenetic protein 2 (BMP-2 or BMP2) is a member of the bone morphogenetic protein (BMP) family and functions as a potent inducer of bone and cartilage development. BMP proteins are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. Bioactive BMP-2 consists of forming a homodimer or a heterodimer with a related BMP, such as BMP-7. BMP-2 signals through type I and type II receptor tyrosine kinases in conjuction with SMAD proteins to directly promote osteoblast differentiation. BMP-2 is also important during cardiac development and supports epicardial cell migration.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	BMP-2A
Accession Number	P12643/P21274/P49001
Source	Genetically modified E.coli
Predicted Molecular Mass	Dimer, 13.0/26.1 kDa (115/230 aa)
AA Sequence	MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR
Formulation	Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 1 EU/µg
Biological Activity (ED₅₀)	Alkaline phosphatase activity induced in ATDC-5 cells	≤ 250 ng/mL

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to -80°C as supplied.

COA Search

Certificates of Analysis Search