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Recombinant Human / Mouse FGF-8

In stock
Catalog ID
800-03
Size Stock SKU Unit Price Qty
5 µg Inquire for Availability 800-03-5UG
$73.00
5 µg (Animal-Free) In Stock 800-03AF-5UG
$79.00
25 µg In Stock 800-03-25UG
$183.00
25 µg (Animal-Free) In Stock 800-03AF-25UG
$200.00
100 µg In Stock 800-03-100UG
$457.00
100 µg (Animal-Free) In Stock 800-03AF-100UG
$504.00
500 µg Inquire for Availability 800-03-500UG
$1,971.00
500 µg (Animal-Free) In Stock 800-03AF-500UG
$2,165.00
1 mg Inquire for Availability 800-03-1MG
$3,284.00
1 mg (Animal-Free) In Stock 800-03AF-1MG
$3,613.00
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Details

Fibroblast growth factor 8 (FGF-8) is a critical mitogenic factor that is required for normal development of the eye, ear, brain, and limb. FGF-8 functions broadly to promote cell proliferation, differentiation, and migration. Overexpression of FGF-8 increases tumor growth and angiogenesis. Human and mouse FGF-8 proteins show 100% homology.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names Androgen-induced growth factor, AIGF, Heparin-binding growth factor 8, HBGF-8, FGF-8b isoform
Accession Number P55075/P37237
Source Genetically modified E.coli
Predicted Molecular Mass Monomer, 22.5 kDa (194 aa)
AA Sequence MQVTVQSSPN FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRGAETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRFEFLNYPPFTR SLRGSQRTWA PEPR
Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution Sterile water at 0.1 mg/mL
Country of Origin USA

 

Specification* Method of Determination Acceptance Criteria
Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
Endotoxin Kinetic LAL ≤ 0.1 EU/µg
Biological Activity (ED50) NR6R-3T3 cell proliferation ≤ 150 ng/mL

 

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage
At or below -20°C
Shelf Life
12 months from date of receipt when stored at -20°C to -80°C as supplied.
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