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Recombinant Human MIP-1 α / CCL3

In stock
Catalog ID
100-15
Size Stock SKU Unit Price Qty
5 µg In Stock 100-15-5UG
$73.00
20 µg In Stock 100-15-20UG
$183.00
100 µg In Stock 100-15-100UG
$457.00
500 µg Inquire for Availability 100-15-500UG
$1,971.00
1 mg Inquire for Availability 100-15-1MG
$3,284.00
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Details

Macrophage inflammatory protein-1 alpha (MIP-1 α), also known as CCL3, is a cytokine produced by macrophages. MIP-1 α binds the chemokine receptors CCR1, CCR4 and CCR5 to induce inflammatory responses, including the recruitment of granulocytes and neutrophil superoxide production. The MIP-1 α and MIP-1 β heterodimer exhibits antiviral activity against the human immunodeficiency virus 1 (HIV-1).

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names CCL3, LD78α
Accession Number P10147
Source Genetically modified E.coli
Predicted Molecular Mass Monomer, 7.8 kDa (70 aa)
AA Sequence ASLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA
Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution Sterile water at 0.1 mg/mL
Country of Origin USA

 

Specification* Method of Determination Acceptance Criteria
Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
Endotoxin Kinetic LAL ≤ 1 EU/µg
Biological Activity (ED50) No biological activity data is available at this time No biological activity data is available at this time

 

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

MIP-1 alpha

Specifications

Storage
At or below -20°C
Shelf Life
12 months from date of receipt when stored at -20°C to -80°C as supplied.
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