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Recombinant Human IL-31

In stock
Catalog ID
100-204
Size Stock SKU Unit Price Qty
5 µg In Stock 100-204-5UG
$73.00
5 µg (Animal-Free) Inquire for Availability 100-204AF-5UG
$79.00
25 µg In Stock 100-204-25UG
$183.00
25 µg (Animal-Free) In Stock 100-204AF-25UG
$200.00
100 µg In Stock 100-204-100UG
$913.00
100 µg (Animal-Free) Inquire for Availability 100-204AF-100UG
$1,004.00
500 µg Inquire for Availability 100-204-500UG
$3,649.00
500 µg (Animal-Free) Inquire for Availability 100-204AF-500UG
$4,014.00
1 mg Inquire for Availability 100-204-1MG
$5,839.00
1 mg (Animal-Free) Inquire for Availability 100-204AF-1MG
$6,422.00
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Details

Interleukin 31 (IL-31) is an immunoregulatory cytokine that is expressed by activated type 2 T helper (Th2) cells. IL-31 signals through a heterodimer receptor consisting of the IL-31 Receptor A (IL-31RA) and the oncostatin M receptor (OSMR), which are expressed on monocytes, epithelial cells, and keratinocytes. IL-31 promotes allergic reactions and inflammatory skin diseases.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C, and avoid repeat freeze thaws.

Technical Specifications

Alternate Names None
Accession Number Q6EBC2
Source Genetically modified E.coli
Predicted Molecular Mass Monomer, 15.8 kDa (141 aa)
AA Sequence SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T
Formulation Lyophilized from a 0.2 µm filtered solution containing 20 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
Product Reconstitution Sterile water at 0.1 mg/mL
Country of Origin USA

 

Specification* Method of Determination Acceptance Criteria
Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
Endotoxin Kinetic LAL ≤ 0.1 EU/µg
Biological Activity (ED50) STAT3 Activation in U-87 MG cells Detectable at ≤ 25 ng/mL

 

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage
At or below -20°C
Shelf Life
12 months from date of receipt when stored at -20°C to-80°C as supplied.
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