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Recombinant Human IGF-I

In stock
Catalog ID
100-34
Size Stock SKU Unit Price Qty
20 µg Inquire for Availability 100-34-20UG
$73.00
    100 µg Inquire for Availability 100-34-100UG
    $183.00
      1 mg Inquire for Availability 100-34-1MG
      $305.00
        5 mg Inquire for Availability 100-34-5MG
        $1,368.00
          20 µg (Animal-Free) Inquire for Availability 100-34AF-20UG
          $79.00
            100 µg (Animal-Free) In Stock 100-34AF-100UG
            $200.00
              1 mg (Animal-Free) Inquire for Availability 100-34AF-1MG
              $335.00
                5 mg (Animal-Free) Inquire for Availability 100-34AF-5MG
                $1,508.00
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                  Details

                  Insulin-like growth factor I (IGF-I) is a growth factor that is produced by the liver. IGF-I production is stimulated by growth hormone (GH). IGF-I binds the insulin-like growth factor I receptor (IGF-I receptor) and the insulin receptor to stimulate systemic body growth. IGF-I is one of the most potent activators of the AKT signaling pathway, which stimulates cell proliferation and inhibits programmed cell death.

                  Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

                  Instructions

                  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

                  Technical Specifications

                  Alternate Names Somatomedin C, mechano growth factor, IGF-IA
                  Accession Number P05019
                  Source Genetically modified E.coli
                  Predicted Molecular Mass Monomer, 7.7 kDa (70 aa)
                  AA Sequence GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA
                  Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
                  Product Reconstitution Sterile water at 0.1 mg/mL
                  Country of Origin USA

                   

                  Specification* Method of Determination Acceptance Criteria
                  Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
                  Endotoxin Kinetic LAL ≤ 0.1 EU/µg
                  Biological Activity (ED50) MCF-7 cell proliferation ≤ 1.5 ng/mL

                   

                  *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

                  Specifications

                  Storage
                  At or below -20°C
                  Shelf Life
                  12 months from date of receipt when stored at -20°C to-80°C as supplied.
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