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Recombinant Human GDNF

In stock
Catalog ID
100-02
Size Stock SKU Unit Price Qty
10 µg In Stock 100-02-10UG
$183.00
    100 µg In Stock 100-02-100UG
    $705.00
      500 µg Inquire for Availability 100-02-500UG
      $3,503.00
        1 mg In Stock 100-02-1MG
        $5,839.00
          10 µg (Animal-Free) In Stock 100-02AF-10UG
          $200.00
            100 µg (Animal-Free) In Stock 100-02AF-100UG
            $773.00
              500 µg (Animal-Free) In Stock 100-02AF-500UG
              $3,857.00
                1 mg (Animal-Free) In Stock 100-02AF-1MG
                $6,422.00
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                  Details

                  Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to activate receptor tyrosine kinase RET signaling. GDNF promotes dopamine uptake, prevents motor neuron apoptosis, and supports the survival and differentiation of neurons.

                  Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

                  Instructions

                  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

                  Technical Specifications

                  Alternate Names ATF-1
                  Accession Number P39905
                  Source Genetically modified E.coli
                  Predicted Molecular Mass Dimer, 15.2/30.4 kDa (135/270 aa)
                  AA Sequence MSPDKQMAVL PRRERNRQAA AANPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCDAAETTY DKILKNLSRN RRLVSDKVGQ ACCRPIAFDD DLSFLDDNLV YHILRKHSAK RCGCI
                  Formulation Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium citrate, 100 mM sodium chloride, pH 4.0
                  Product Reconstitution Sterile water at 0.1 mg/mL
                  Country of Origin USA

                   

                  Specification* Method of Determination Acceptance Criteria
                  Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
                  Endotoxin Kinetic LAL ≤ 0.1 EU/µg
                  Biological Activity (ED50) C6 proliferation ≤ 3 µg/mL; ≥ 3.3 x 102 units/mg

                   

                  *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

                  Specifications

                  Storage
                  At or below -20°C
                  Shelf Life
                  12 months from date of receipt when stored at -20°C to-80°C as supplied.
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