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Recombinant Human β-NGF

In stock
Catalog ID
100-38
Size Stock SKU Unit Price Qty
5 µg In Stock 100-38-5UG
$73.00
5 µg (Animal-Free) In Stock 100-38AF-5UG
$79.00
20 µg In Stock 100-38-20UG
$183.00
20 µg (Animal-Free) In Stock 100-38AF-20UG
$200.00
100 µg In Stock 100-38-100UG
$457.00
100 µg (Animal-Free) In Stock 100-38AF-100UG
$504.00
500 µg Inquire for Availability 100-38-500UG
$1,971.00
500 µg (Animal-Free) In Stock 100-38AF-500UG
$2,165.00
1 mg In Stock 100-38-1MG
$3,284.00
1 mg (Animal-Free) In Stock 100-38AF-1MG
$3,613.00
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Details

Nerve growth factor beta (β-NGF) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. β-NGF signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. β-NGF is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat β-NGF proteins are cross-reactive.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names beta-NGF
Accession Number P01138
Source Genetically modified E.coli
Predicted Molecular Mass Noncovalent Homodimer, 13.6 kDa (121 aa)
AA Sequence MSSSHPIFHR GEFSVCDSVS VWVGDKTTAT DIKGKEVMVL GEVNINNSVF KQYFFETKCR DPNPVDSGCR GIDSKHWNSY CTTTHTFVKA LTMDGKQAAW RFIRIDTACV CVLSRKAVRR A
Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution Sterile water at 0.1 mg/mL
Country of Origin USA

 

Specification* Method of Determination Acceptance Criteria
Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
Endotoxin Kinetic LAL ≤ 0.1 EU/µg
Biological Activity (ED50) TF-1 cell proliferation ≤ 5 ng/mL

 

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

beta-NGF beta NGF

Specifications

Storage
At or below -20°C
Shelf Life
12 months from date of receipt when stored at -20°C to-80°C as supplied.
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