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Recombinant Human BDNF

In stock
Catalog ID
100-01
Size Stock SKU Unit Price Qty
10 µg In Stock 100-01-10UG
$183.00
10 µg (Animal-Free) In Stock 100-01AF-10UG
$200.00
100 µg In Stock 100-01-100UG
$705.00
100 µg (Animal-Free) In Stock 100-01AF-100UG
$779.00
500 µg In Stock 100-01-500UG
$3,503.00
500 µg (Animal-Free) In Stock 100-01AF-500UG
$3,857.00
1 mg In Stock 100-01-1MG
$5,839.00
1 mg (Animal-Free) In Stock 100-01AF-1MG
$6,422.00
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Details

Brain-derived neurotrophic factor (BDNF) is a nerve growth factor that binds two receptors, the low-affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase B (TrkB), to support neuron growth and survival. BDNF expression in the hippocampus is essential for long-term memory storage and learning. Human, mouse, rat, and pig BDNF are cross-reactive.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names None
Accession Number P23560
Source Genetically modified E.coli
Predicted Molecular Mass Noncovalent Homodimer, 13.6/27.3 kDa (120/240 aa)
AA Sequence MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR
Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution Sterile water at 0.1 mg/mL
Country of Origin USA

 

Specification* Method of Determination Acceptance Criteria
Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
Endotoxin Kinetic LAL ≤ 0.1 EU/µg
Biological Activity (ED50) Proliferation of a neuroblastoma cell line stably expressing TrkB (BR6) ≤ 40 ng/mL; 2.5 x 104 units/mg

 

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

Specifications

Storage
At or below -20°C
Shelf Life
12 months from date of receipt when stored at -20°C to-80°C as supplied.
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