Join Our Mailing List Today!

NOTICE: Online ordering will be disabled 1/27-2/3. Learn More.

Recombinant Equine PDGF-BB

In stock
Catalog ID
400-17
Size Stock SKU Unit Price Qty
5 µg Inquire for Availability 400-17-5UG
$73.00
    20 µg Inquire for Availability 400-17-20UG
    $183.00
      100 µg Inquire for Availability 400-17-100UG
      $517.00
        500 µg Inquire for Availability 400-17-500UG
        $2,554.00
          1 mg Inquire for Availability 400-17-1MG
          $4,258.00
            5 µg (Animal-Free) Inquire for Availability 400-17AF-5UG
            $79.00
              20 µg (Animal-Free) In Stock 400-17AF-20UG
              $200.00
                100 µg (Animal-Free) In Stock 400-17AF-100UG
                $566.00
                  500 µg (Animal-Free) Inquire for Availability 400-17AF-500UG
                  $2,811.00
                    1 mg (Animal-Free) Inquire for Availability 400-17AF-1MG
                    $4,683.00
                      reset
                      Details

                      Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β, and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β.

                      Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

                      Instructions

                      Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C, and avoid repeat freeze thaws.

                      Technical Specifications

                      Alternate Names GDGF, ODGF
                      Accession Number XP_005606703
                      Source Genetically modified E.coli
                      Predicted Molecular Mass Dimer, 24.8 kDa (110/220 aa)
                      AA Sequence MSLGSLAVAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRHVQ CRPTQVQLRP VQVRKIEIVR KKPTFKKATV TLEDHLACKC ETVGAARPVT
                      Formulation Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, pH 7.5
                      Product Reconstitution Sterile 20 mM HCl at 0.1 mg/mL
                      Country of Origin USA

                       

                      Specification* Method of Determination Acceptance Criteria
                      Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
                      Endotoxin Kinetic LAL ≤ 0.1 EU/µg
                      Biological Activity (ED50) NR6R-3T3 cell proliferation ≤ 30 ng/mL

                       

                      *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

                      Specifications

                      Storage
                      At or below -20°C
                      Shelf Life
                      12 months from date of receipt when stored at -20°C to -80°C as supplied.
                      © 2024 FUJIFILM Irvine Scientific. All rights reserved.