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Recombinant Porcine IL-4

In stock
Catalog ID
400-10
Size Stock SKU Unit Price Qty
5 µg In Stock 400-10-5UG
$73.00
    20 µg In Stock 400-10-20UG
    $183.00
      100 µg In Stock 400-10-100UG
      $790.00
        500 µg In Stock 400-10-500UG
        $3,284.00
          1 mg In Stock 400-10-1MG
          $5,839.00
            5 µg (Animal-Free) Inquire for Availability 400-10AF-5UG
            $79.00
              20 µg (Animal-Free) Inquire for Availability 400-10AF-20UG
              $200.00
                100 µg (Animal-Free) Inquire for Availability 400-10AF-100UG
                $870.00
                  500 µg (Animal-Free) Inquire for Availability 400-10AF-500UG
                  $3,613.00
                    1 mg (Animal-Free) Inquire for Availability 400-10AF-1MG
                    $6,422.00
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                      Details

                      Interleukin 4 (IL-4) is an immunomodulatory cytokine that functions to induce naïve helper T cells to differentiate into type 2 T helper (Th2) cells. Th2 cells subsequently produce more IL-4 in a positive feedback loop. IL-4 also promotes immunoglobulin IgG to IgE isotype switching on B cells. IL-4 binds the IL-4Rα receptor to activate STAT6 signaling.

                      Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

                      Instructions

                      Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. 

                      Technical Specifications

                      Alternate Names B-cell stimulatory factor-1, BSF-1, BCDF, BCGF
                      Accession Number Q04745
                      Source Genetically modified E.coli
                      Predicted Molecular Mass Monomer, 12.7 kDa (110 aa)
                      AA Sequence MHKCDITLQE IIKTLNILTA RKNSCMELPV TDVFAAPENT TEKETFCRAS TVLRHIYRHH TCMKSLLSGL DRNLSSMANM TCSVHEAKKS TLKDFLERLK TIMKEKYSKC
                      Formulation Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, pH 7.5
                      Product Reconstitution Sterile water at 0.1 mg/mL
                      Country of Origin USA

                       

                      Specification* Method of Determination Acceptance Criteria
                      Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
                      Endotoxin Kinetic LAL ≤ 0.1 EU/µg
                      Biological Activity (ED50) TF-1 cell proliferation ≤ 2 ng/mL

                       

                      *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

                      Specifications

                      Storage
                      At or below -20°C
                      Shelf Life
                      12 months from date of receipt when stored at -20°C to -80°C as supplied.
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