Recombinant Mouse M-CSF

In stock

Catalog ID

200-08

Size	Stock	SKU	Unit Price
10 µg	In Stock	200-08-10UG	$183.00
100 µg	In Stock	200-08-100UG	$590.00
500 µg	In Stock	200-08-500UG	$2,846.00
1 mg	In Stock	200-08-1MG	$4,744.00
10 µg (Animal-Free)	In Stock	200-08AF-10UG	$200.00
100 µg (Animal-Free)	In Stock	200-08AF-100UG	$651.00
500 µg (Animal-Free)	Inquire for Availability	200-08AF-500UG	$3,132.00
1 mg (Animal-Free)	In Stock	200-08AF-1MG	$5,219.00

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Details

Macrophage colony stimulating factor (M-CSF) is a hematopoietic growth factor that is widely produced by a variety of cells. M-CSF stimulates the proliferation and differentiation of hematopoietic stem cells into monocyte and macrophage cell types. M-CSF also acts through the colony stimulating factor 1 receptor (CSF1R) to modulate processes involved in immunology, bone metabolism, fertility, and pregnancy. Human M-CSF shows activity on mouse cells; however, mouse M-CSF shows no activity on human cells.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	MGI-1M, CSF-1
Accession Number	P07141
Source	Genetically modified E.coli
Predicted Molecular Mass	Dimer, 18.2/36.4 kDa (156/312 aa)
AA Sequence	MKEVSEHCSH MIGNGHLKVL QQLIDSQMET SCQIAFEFVD QEQLDDPVCY LKKAFFLVQD IIDETMRFKD NTPNANATER LQELSNNLNS CFTKDYEEQN KACVRTFHET PLQLLEKIKN FFNETKNLLE KDWNIFTKNC NNSFAKCSSR DVVTKP
Formulation	Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	NFS-60 cell proliferation	≤ 10 ng/mL

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to-80°C as supplied.

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