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Recombinant Mouse IFN-γ

In stock
Catalog ID
200-16
Size Stock SKU Unit Price Qty
20 µg In Stock 200-16-20UG
$73.00
    100 µg In Stock 200-16-100UG
    $183.00
      250 µg In Stock 200-16-250UG
      $419.00
        500 µg In Stock 200-16-500UG
        $700.00
          1 mg Inquire for Availability 200-16-1MG
          $1,217.00
            20 µg (Animal-Free) Inquire for Availability 200-16AF-20UG
            $79.00
              100 µg (Animal-Free) In Stock 200-16AF-100UG
              $200.00
                250 µg (Animal-Free) In Stock 200-16AF-250UG
                $462.00
                  500 µg (Animal-Free) In Stock 200-16AF-500UG
                  $766.00
                    1 mg (Animal-Free) Inquire for Availability 200-16AF-1MG
                    $1,338.00
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                      Details

                      Interferon gamma (IFN-γ) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFN-γ is produced by T cells and natural killer cells following antigen-specific activation. IFN-γ binds IFN-γ receptors (IFN-γ R1 and IFN-γ R2), which are expressed on most immune cells, to activate the JAK-STAT pathway. IFN-γ-induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules. Mouse IFN-γ is not cross-reactive with human IFN-γ.

                      Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

                      Instructions

                      Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. If a precipitate is observed, centrifuge the solution thoroughly and use only the soluble fraction (removing it from the precipitate). A 10% overfill has been added to compensate for any loss of protein in the precipitate. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.  

                      Technical Specifications

                      Alternate Names Type II interferon, T cell interferon, Immune Interferon, MAF
                      Accession Number P01580
                      Source Genetically modified E.coli
                      Predicted Molecular Mass Monomer, 15.7 kDa (134 aa)
                      AA Sequence MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC
                      Formulation Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
                      Product Reconstitution Sterile water at 0.1 mg/mL
                      Country of Origin USA

                       

                      Specification* Method of Determination Acceptance Criteria
                      Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
                      Endotoxin Kinetic LAL ≤ 0.1 EU/µg
                      Biological Activity (ED50) Viral CPE assay using EMC virus on L929 cells ≤ 1 ng/mL; ≥ 1.0 x 106 units/mg

                       

                      *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

                      IFN-gamma IFN gamma

                      Specifications

                      Storage
                      At or below -20°C
                      Shelf Life
                      12 months from date of receipt when stored at -20°C to -80°C as supplied.
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