Join Our Mailing List Today!

NOTICE: Online ordering will be disabled 1/27-2/3. Learn More.

Recombinant Human TGF-β 1

In stock
Catalog ID
100-39
Size Stock SKU Unit Price Qty
5 µg In Stock 100-39-5UG
$90.00
    20 µg In Stock 100-39-20UG
    $330.00
      100 µg In Stock 100-39-100UG
      $1,210.00
        500 µg In Stock 100-39-500UG
        $3,643.00
          reset
          Details

          Transforming growth factor-beta 1 (TGF-β 1) is a member of the TGF-beta superfamily of cytokines. Members of this family exhibit regulatory activity in immunity, proliferation, adhesion, migration, and growth inhibition pathways. TGF-β 1signals through SMAD proteins via the TGF-βRI and TGF-βRII receptors.

          Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

          Instructions

          Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

          Technical Specifications

          Alternate Names Differentiation inhibiting factor, cartilage-inducing factor
          Accession Number P01137
          Source Genetically modified CHO cells
          Predicted Molecular Mass Dimer, 12.8/25.6 kDa (112/224 aa)
          AA Sequence ALDTNYCFSS TEKNCCVRQL YIDFRKDLGW KWIHEPKGYH ANFCLGPCPY IWSLDTQYSK VLALYNQHNP GASAAPCCVP QALEPLPIVY YVGRKPKVEQ LSNMIVRSCK CS
          Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1 % trifluoroacetic acid (TFA) and Trehalose in a 20:1 Trehalose to protein ratio
          Product Reconstitution Sterile 10 mM HCl at 0.1 mg/mL
          Country of Origin USA

           

          Specification* Method of Determination Acceptance Criteria
          Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
          Endotoxin Kinetic LAL ≤ 0.1 EU/µg
          Biological Activity (ED50) Inhibition of IL-4-induced HT-2 cell proliferation ≤ 0.5 ng/mL

           

          *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

          TGF beta TGF-beta

          Specifications

          Storage
          At or below -20°C
          Shelf Life
          12 months from date of receipt when stored at -20°C to -80°C as supplied.
          © 2024 FUJIFILM Irvine Scientific. All rights reserved.