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Recombinant Human PlGF-3

In stock
Catalog ID
100-198
Size Stock SKU Unit Price Qty
5 µg Inquire for Availability 100-198-5UG
$73.00
    25 µg In Stock 100-198-25UG
    $183.00
      100 µg In Stock 100-198-100UG
      $590.00
        500 µg Inquire for Availability 100-198-500UG
        $1,971.00
          1 mg Inquire for Availability 100-198-1MG
          $3,284.00
            5 µg (Animal-Free) In Stock 100-198AF-5UG
            $79.00
              25 µg (Animal-Free) In Stock 100-198AF-25UG
              $200.00
                100 µg (Animal-Free) In Stock 100-198AF-100UG
                $651.00
                  500 µg (Animal-Free) Inquire for Availability 100-198AF-500UG
                  $2,165.00
                    1 mg (Animal-Free) Inquire for Availability 100-198AF-1MG
                    $3,613.00
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                      Details

                      Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family and promotes endothelial cell growth and angiogenesis. PlGF is secreted as a homodimer and may also form a heterodimer with VEGF. PlGF is detected in the placenta, heart, lungs, thyroid, and adipose tissues. Circulating PlGF levels are correlated with colorectal and renal cancers, as well as atherosclerosis and ischemic heart disease. There are four alternatively spliced PlGF isoforms (PlGF-1, PlGF-2, PlGF-3, and PlGF-4), each with unique secretion patterns and heparin-binding affinities. PlGF-3 lacks a heparin-binding domain and signals through the VEGFR-1 receptor. 

                      Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

                      Instructions

                      Centrifuge vial before opening.  Suspend the product by gently pipetting the above recommended solution down the sides of the vial.  DO NOT VORTEX.  Allow several minutes for complete reconstitution.  For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.   

                      Technical Specifications

                      Alternate Names None
                      Accession Number P49763
                      Source Genetically modified E.coli
                      Predicted Molecular Mass Dimer, 22.9/45.8 kDa (204/408 aa)
                      AA Sequence MLPAVPPQQW ALSAGNGSSE VEVVPFQEVW GRSYCRALER LVDVVSEYPS EVEHMFSPSC VSLLRCTGCC GDENLHCVPV ETANVTMQLL KIRSGDRPSY VELTFSQHVR CECRHSPGRQ SPDMPGDFRA DAPSFLPPRR SLPMLFRMEW GCALTGSQSA VWPSSPVPEE IPRMHPGRNG KKQQRKPLRE KMKPERCGDA VPRR
                      Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
                      Product Reconstitution Sterile water at 0.1 mg/mL
                      Country of Origin USA

                       

                      Specification* Method of Determination Acceptance Criteria
                      Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
                      Endotoxin Kinetic LAL ≤ 0.1 EU/µg
                      Biological Activity (ED50) No biological activity data is available at this time No biological activity data is available at this time

                       

                      *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

                      Specifications

                      Storage
                      At or below -20°C
                      Shelf Life
                      12 months from date of receipt when stored at -20°C to -80°C as supplied.
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