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Recombinant Human MIP-1 β / CCL4

In stock
Catalog ID
100-134
Size Stock SKU Unit Price Qty
10 µg Inquire for Availability 100-134-10UG
$183.00
    100 µg Inquire for Availability 100-134-100UG
    $457.00
      500 µg Inquire for Availability 100-134-500UG
      $1,971.00
        1 mg Inquire for Availability 100-134-1MG
        $3,284.00
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          Details

          Macrophage inflammatory protein-1 beta (MIP-1 β), also known as CCL4, is produced by macrophages and functions as a mitogen-inducible cytokine. MIP-1 β signals through the chemokine receptor CCR5 to chemoattract immune cells. MIP-1 β induces inflammatory responses, including neutrophil superoxide production. The MIP-1 β and MIP-1 α heterodimer exhibits antiviral activity against the human immunodeficiency virus 1 (HIV-1).

          Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

          Instructions

          Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

          Technical Specifications

          Alternate Names CCL4, ACT-2
          Accession Number P13236
          Source Genetically modified E.coli
          Predicted Molecular Mass Monomer, 7.8 kDa (69 aa)
          AA Sequence APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESWVQ EYVYDLELN
          Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
          Product Reconstitution Sterile water at 0.1 mg/mL
          Country of Origin USA

           

          Specification* Method of Determination Acceptance Criteria
          Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
          Endotoxin Kinetic LAL ≤ 1 EU/µg
          Biological Activity (ED50) No biological activity data is available at this time No biological activity data is available at this time

           

          *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

          MIP-1 beta

          Specifications

          Storage
          At or below -20°C
          Shelf Life
          12 months from date of receipt when stored at -20°C to -80°C as supplied.
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