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Recombinant Human IP-10 / CXCL10

In stock
Catalog ID
100-127
Size Stock SKU Unit Price Qty
5 µg In Stock 100-127-5UG
$73.00
    25 µg In Stock 100-127-25UG
    $183.00
      100 µg In Stock 100-127-100UG
      $457.00
        500 µg Inquire for Availability 100-127-500UG
        $1,971.00
          1 mg In Stock 100-127-1MG
          $3,284.00
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            Details

            Interferon gamma-induced protein 10 (IP-10), or CXCL10, is a chemokine secreted by monocytes, endothelial cells and fibroblasts in response to interferon gamma (IFN-ɣ). IP-10 functions as a chemoattractant for activated T cells, monocytes, dendritic, and natural killer (NK) cells that express the G protein-coupled receptor CXCR3. IP-10 is an important factor in autoimmune diseases such as Hashimoto’s thyroiditis, Graves’ disease, and Type 1 diabetes mellitus.

            Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

            Instructions

            Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

            Technical Specifications

            Alternate Names CXCL10, CRG-2
            Accession Number P02778
            Source Genetically modified E.coli
            Predicted Molecular Mass Monomer, 8.6 kDa (77 aa)
            AA Sequence VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK ERSKRSP
            Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
            Product Reconstitution Sterile water at 0.1 mg/mL
            Country of Origin USA

             

            Specification* Method of Determination Acceptance Criteria
            Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
            Endotoxin Kinetic LAL ≤ 1 EU/µg
            Biological Activity (ED50) No biological activity data is available at this time No biological activity data is available at this time

             

            *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

            Specifications

            Storage
            At or below -20°C
            Shelf Life
            12 months from date of receipt when stored at -20°C to-80°C as supplied.
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