Recombinant Human IL-31

In stock

Catalog ID

100-204

Size	Stock	SKU	Unit Price
5 µg	In Stock	100-204-5UG	$73.00
25 µg	In Stock	100-204-25UG	$183.00
100 µg	In Stock	100-204-100UG	$913.00
500 µg	Inquire for Availability	100-204-500UG	$3,649.00
1 mg	Inquire for Availability	100-204-1MG	$5,839.00
5 µg (Animal-Free)	Inquire for Availability	100-204AF-5UG	$79.00
25 µg (Animal-Free)	In Stock	100-204AF-25UG	$200.00
100 µg (Animal-Free)	Inquire for Availability	100-204AF-100UG	$1,004.00
500 µg (Animal-Free)	Inquire for Availability	100-204AF-500UG	$4,014.00
1 mg (Animal-Free)	Inquire for Availability	100-204AF-1MG	$6,422.00

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Details

Interleukin 31 (IL-31) is an immunoregulatory cytokine that is expressed by activated type 2 T helper (Th2) cells. IL-31 signals through a heterodimer receptor consisting of the IL-31 Receptor A (IL-31RA) and the oncostatin M receptor (OSMR), which are expressed on monocytes, epithelial cells, and keratinocytes. IL-31 promotes allergic reactions and inflammatory skin diseases.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C, and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	None
Accession Number	Q6EBC2
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 15.8 kDa (141 aa)
AA Sequence	SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T
Formulation	Lyophilized from a 0.2 µm filtered solution containing 20 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	STAT3 Activation in U-87 MG cells	Detectable at ≤ 25 ng/mL

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to-80°C as supplied.

FAQs

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