Recombinant Human IL-17F

In stock

Catalog ID

100-152

Size	Stock	SKU	Unit Price
5 µg	In Stock	100-152-5UG	$73.00
25 µg	In Stock	100-152-25UG	$183.00
100 µg	In Stock	100-152-100UG	$457.00
500 µg	Inquire for Availability	100-152-500UG	$1,971.00
1 mg	Inquire for Availability	100-152-1MG	$3,284.00
5 µg (Animal-Free)	Inquire for Availability	100-152AF-5UG	$79.00
25 µg (Animal-Free)	In Stock	100-152AF-25UG	$200.00
100 µg (Animal-Free)	In Stock	100-152AF-100UG	$504.00
500 µg (Animal-Free)	Inquire for Availability	100-152AF-500UG	$2,165.00
1 mg (Animal-Free)	In Stock	100-152AF-1MG	$3,613.00

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Details

Interleukin 17F (IL-17F), a member of the IL-17 cytokine family, is secreted by activated CD4+ T cells and monocytes. IL-17F binds the IL-17 receptor related molecule, IL17RC, to promote the production of the interleukin 6 (IL-6), interleukin 8 (IL-8), and granulocyte macrophage colony-stimulating factor (GM-CSF) cytokines. IL-17F also functions to regulate matrix turnover rates, inhibit endothelial cell angiogenesis, and induce the endothelial cell expression of interleukin 2 (IL-2), monocyte chemoattractant protein-1 (MCP-1), and transforming growth factor beta 1 (TGF-β1).

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	None
Accession Number	Q96PD4
Source	Genetically modified E.coli
Predicted Molecular Mass	Dimer, 15.0/30.1 kDa (134/268 aa)
AA Sequence	MRKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHVQ
Formulation	Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	Production of IL-6 from mouse 3T3 cells	≤ 100 ng/mL; ≥ 1.0 x 10⁴ units/mg

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to -80°C as supplied.

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