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Recombinant Human HB-EGF

In stock
Catalog ID
Size Stock SKU Unit Price Qty
10 µg In Stock 100-180-10UG
    50 µg In Stock 100-180-50UG
      100 µg In Stock 100-180-100UG
        500 µg In Stock 100-180-500UG
          1 mg In Stock 100-180-1MG
            10 µg (Animal-Free) In Stock 100-180AF-10UG
              50 µg (Animal-Free) In Stock 100-180AF-50UG
                100 µg (Animal-Free) In Stock 100-180AF-100UG
                  500 µg (Animal-Free) Inquire for Availability 100-180AF-500UG
                    1 mg (Animal-Free) In Stock 100-180AF-1MG

                      Heparin-binding EGF-like growth factor (HB-EGF) is a member of the epidermal growth factor (EGF) family and is expressed by monocytes and macrophages. HB-EGF is the predominant growth factor involved in epithelialization during wound healing. HB-EGF signals through the receptor tyrosine kinase ErbB2 to maintain adult heart homeostasis, and promotes cardiac valve development through binding in high affinity to the epidermal growth factor receptor (EGFR). HB-EGF binds the the ErbB4 receptor tyrosine kinase to mediate implantation of the human blastocyst. HB-EGF also functions as a potent mitogen for fibroblasts and smooth muscle cells.

                      Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.


                      Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

                      Technical Specifications

                      Alternate Names HBEGF, Diphtheria toxin receptor, DT-R
                      Accession Number Q99075
                      Source Genetically modified E.coli
                      Predicted Molecular Mass Monomer, 9.9 kDa (87 aa)
                      Formulation Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, pH 7.5
                      Product Reconstitution Sterile water at 0.1 mg/mL
                      Country of Origin USA


                      Specification* Method of Determination Acceptance Criteria
                      Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
                      Endotoxin Kinetic LAL ≤ 0.1 EU/µg
                      Biological Activity (ED50) 3T3 cell proliferation ≤ 1 ng/mL; ≥ 1.0 x 106 units/mg


                      *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.


                      At or below -20°C
                      Shelf Life
                      12 months from date of receipt when stored at -20°C to-80°C as supplied.
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