Recombinant Human GDF-15

In stock

Catalog ID

100-171

Size	Stock	SKU	Unit Price
5 µg	Inquire for Availability	100-171-5UG	$73.00
20 µg	In Stock	100-171-20UG	$183.00
100 µg	In Stock	100-171-100UG	$517.00
500 µg	In Stock	100-171-500UG	$2,554.00
1 mg	Inquire for Availability	100-171-1MG	$4,258.00
5 µg (Animal-Free)	Inquire for Availability	100-171AF-5UG	$79.00
20 µg (Animal-Free)	Inquire for Availability	100-171AF-20UG	$200.00
100 µg (Animal-Free)	Inquire for Availability	100-171AF-100UG	$566.00
500 µg (Animal-Free)	Inquire for Availability	100-171AF-500UG	$2,811.00
1 mg (Animal-Free)	Inquire for Availability	100-171AF-1MG	$4,683.00

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Details

Growth differentiation factor 15 (GDF-15) is a member of the transforming growth factor beta (TGF-β) family and is made by the placenta and cardiovascular tissues. GDF-15 regulates inflammatory and apoptotic pathways during cellular stress and injury. GDF-15 is emerging as a biomarker of early heart disease, such that increased levels of circulating GDF-15 are associated with an increased risk of developing heart failure.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	MIC-1, Placental TGF-β, Prostate differentiation factor
Accession Number	Q99988
Source	Genetically modified E.coli
Predicted Molecular Mass	Dimer, 12.4/24.8 kDa (113/226 aa)
AA Sequence	MARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLIQKTDTGVSLQ TYDDLLAKDC HCI
Formulation	Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	No biological activity data is available at this time	No biological activity data is available at this time

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to-80°C as supplied.

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