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Recombinant Human BD-3

In stock
Catalog ID
Size Stock SKU Unit Price Qty
5 µg In Stock 100-192-5UG
    20 µg In Stock 100-192-20UG
      100 µg In Stock 100-192-100UG
        500 µg In Stock 100-192-500UG
          1 mg In Stock 100-192-1MG

            Beta-Defensin 3 (BD-3), also known as DEFB-3, is a member of the defensin class of antimicrobial peptides. Beta defensins exert host defense responses against viruses, bacteria, and fungi through the binding and permeabilizing of microbial membranes. BD-3 expression is stimulated by interferon-gamma and is an important molecule during adaptive immunity. BD-3 functions to activate monocytes and mast cells, and has antibacterial functions towards Gram-negative and Gram-positive bacteria. Further, BD-3 blocks human immunodeficiency virus type 1 (HIV-1) replication through the downregulation of the HIV-1 co-receptor, CXCR4.

            Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.


            Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

            Technical Specifications

            Alternate Names DEFB-3
            Accession Number P81534
            Source Genetically modified E.coli
            Predicted Molecular Mass Monomer, 5.2 kDa (45 aa)
            Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
            Product Reconstitution Sterile 10 mM acetic acid at 0.1 mg/mL
            Country of Origin USA


            Specification* Method of Determination Acceptance Criteria
            Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
            Endotoxin Kinetic LAL ≤ 0.1 EU/µg
            Biological Activity (ED50) No biological activity data is available at this time No biological activity data is available at this time


            *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.


            At or below -20°C
            Shelf Life
            12 months from date of receipt when stored at -20°C to -80°C as supplied.
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