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Recombinant Equine VEGF-165

In stock
Catalog ID
400-18
Size Stock SKU Unit Price Qty
5 µg In Stock 400-18-5UG
$73.00
    20 µg Inquire for Availability 400-18-20UG
    $183.00
      100 µg Inquire for Availability 400-18-100UG
      $517.00
        500 µg Inquire for Availability 400-18-500UG
        $2,554.00
          1 mg Inquire for Availability 400-18-1MG
          $4,258.00
            5 µg (Animal-Free) Inquire for Availability 400-18AF-5UG
            $79.00
              20 µg (Animal-Free) Inquire for Availability 400-18AF-20UG
              $200.00
                100 µg (Animal-Free) Inquire for Availability 400-18AF-100UG
                $566.00
                  500 µg (Animal-Free) Inquire for Availability 400-18AF-500UG
                  $2,811.00
                    1 mg (Animal-Free) Inquire for Availability 400-18AF-1MG
                    $4,683.00
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                      Details

                      Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.

                      Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

                      Instructions

                      Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C, and avoid repeat freeze thaws.

                      Technical Specifications

                      Alternate Names VEGF-A, VPF, glioma-derived endothelial cell mitogen
                      Accession Number Q9GKR0
                      Source Genetically modified E.coli
                      Predicted Molecular Mass Dimer, 19.3 / 38.6 kDa (165/330 aa)
                      AA Sequence MAPMAEGEHK THEVVKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TAEFNITMQI MRIKPHQSQH IGEMSFLQHS KCECRPKKDK ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
                      Formulation Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, pH 7.5
                      Product Reconstitution Sterile 20 mM HCl at 0.1 mg/mL
                      Country of Origin USA

                       

                      Specification* Method of Determination Acceptance Criteria
                      Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
                      Endotoxin Kinetic LAL ≤ 0.1 EU/µg
                      Biological Activity (ED50) HUVEC Proliferation ≤ 10 ng/mL

                       

                      *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

                      Specifications

                      Storage
                      At or below -20°C
                      Shelf Life
                      12 months from date of receipt when stored at -20°C to-80°C as supplied.
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