Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) is a pleiotropic cytokine and a member of a family of endogenous cytokines of the hematopoietic system. GM-CSF is produced as a response to immune or inflammatory stimuli by monocytes, T cells, macrophages as well as fibroblasts. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages. Human and mouse GM-CSF show no crossreactivity. Recombinant GM-CSF is a non-glycosylated protein containing 127 amino acids, with a molecular weight of 14.5 kDa.
Accession Number: P04141
Synonyms: CSF-2, Pluripoietin-α, MGI1GM
Purity: ≥ 95% purity. Determined by HPLC, reducing and non-reducing SDS-PAGE, and UV spectroscopy
Bioactivity: ED50 typically less than 0.5 ng/mL. ED50 determined by dose dependent proliferation of human TF1 cells.
Animal component-free and carrier-free
Custom packaging available
For research or further manufacturing use only.
Also available in other sizes.
This product is shipped with dry ice. Upon receipt, store the medium at or below -10°C in a manual defrost freezer.