PRIME-XV MSC Expansion XSFM
Human mesenchymal stem cell / mesenchymal stromal cell (MSC) expansion xeno-free, serum-free medium
- Maintains MSC quality after extended culture
- Supports expansion of MSCs derived from human adipose, human bone marrow, and human umbilical cord
- Xeno-free and serum-free formulation for lot-to-lot consistency
- Manufactured under cGMP conditions
- Mycoplasma USP <63> testing is standard on all lots
- Drug Master File (DMF) registration
- Available in 250 mL and 1 L packaging
- Custom packaging and modifications available
For research or further manufacturing use only.
Contact us for international pricing.
This product is shipped with dry ice. Upon receipt, store the medium at or below -10°C in a manual defrost freezer.
Handle using aseptic techniques to avoid contamination. Unopened liquid medium is stable for 24 months from date of manufacture, as indicated on the label.
OPEN ACCESS: Basoli, Valentina et al. (2021). Effect of expansion media and fibronectin coating on growth and chondrogenic differentiation of human bone marrow-derived mesenchymal stromal cells. Scientific Reports.
OPEN ACCESS: Sun, Jessica M. et al. (2020) Infusion of human umbilical cord tissue mesenchymal stromal cells in children with autism spectrum disorder. STEM CELLS Transl Med.
OPEN ACCESS: Muraya, Koji et al. (2019) Enhancement of cellular adhesion and proliferation in human mesenchymal stromal cells by the direct addition of recombinant collagen I peptide to the culture medium. BioResearch.
OPEN ACCESS: Mochizuki, Mai et al. (2020) Type I collagen facilitates safe and reliable expansion of human dental pulp stem cells in xenogeneic serum-free culture. Stem Cell Research & Therapy.
OPEN ACCESS: Mellott, Stuart B et al. (2019) Finding Preferred Food for Mesenchymal Stem Cells: A Media Comparison.
OPEN ACCESS: Manferdini, C. et al. (2020) Specific effects of osteoarthritic milieu and hypoxic conditions on adipose mesenchymal stromal cell migration and cytokine receptors expression. Cytotherapy.
OPEN ACCESS: Harrison Richard P. et al. (2018) Cell therapy-processing economics: small-scale microfactories as a stepping stone toward large-scale macrofactories. Regenerative medicine.
OPEN ACCESS: Fernández, A. López et al. (2020) Successful scale up expansion of Wharton's jelly mesenchymal stromal cells in different commercial xeno-free and serum-free media. Cytotherapy.
OPEN ACCESS: Lopes, Vanda S. et al. (2018) A Xeno-Free, Serum-Free Expansion Medium for Ex-vivo Expansion and Maintenance of Major Human Tissue-Derived Mesenchymal Stromal Cells. Transl Biomed. Vol.9 No.2:146. doi: 10.21767/2172-0479.100146
OPEN ACCESS: Motoike, Souta et al. (2019) Clumps of Mesenchymal Stem Cell/Extracellular Matrix Complexes Generated with Xeno-Free Conditions Facilitate Bone Regeneration via Direct and Indirect Osteogenesis. Motoike, Souta et al. “Clumps of Mesenchymal St
OPEN ACCESS: Mitsuzawa, Sadaki et al. (2019) Pro-angiogenic scaffold-free Bio three-dimensional conduit developed from human induced pluripotent stem cell-derived mesenchymal stem cells promotes peripheral nerve regeneration. Scientific Reports.
OPEN ACCESS: Qu, C. et al. (2020) Evaluation of growth, stemness, and angiogenic properties of dental pulp stem cells cultured in cGMP xeno-/serum-free medium. Cell and Tissue Research.
OPEN ACCESS: Mochizuki, Mai and Nakahara, Taka. (2018) Establishment of xenogeneic serum-free culture methods for handling human dental pulp stem cells using clinically oriented in-vitro and in-vivo conditions. Stem Cell Research & Therapy.
Noldner et at. Expanding and Streamlining Cord Tissue‐Derived Mesenchymal Stem Cells Manufacture. Stem Cells Transl Med. 2018 Sep; 7(Suppl Suppl 1).