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Catalog ID

Chemically defined, animal component-free medium for natural killer (NK) and NKT cell expansion optimized to deliver cell growth while maintaining NK and NKT cell functionality and potency.

Size Stock SKU Unit Price Qty
1 L Inquire for Availability 91215-1L

PRIME-XV NK Cell CDM is the first commercial chemically defined animal component-free medium for the ex vivo expansion of natural killer cells.

Designed for use in NK and NKT cell-based immunotherapy research and translational applications, this advanced formulation delivers growth while maintaining NK and NKT cell functionality and potency—without the need for serum supplementation.

Key benefits include:

  • Efficient ex vivo expansion of NK and NKT cells in a chemically defined medium (CDM) designed to deliver high lot-to-lot consistency
  • Animal component-free (ACF) formulation helps to minimize the risk from adventitious agents
  • Formulated to support NK and NKT cells derived from peripheral blood mononuclear cells (PBMCs)

Designed to facilitate a seamless transition from the laboratory to further manufacturing use:

  • cGMP manufactured for quality, consistency, and scalability
  • Robust raw material controls and supply chain management
  • Traceability documentation provided, including Certificates of Analysis, Certificates of Origin, and a Drug Master File (DMF) filed with the U.S. FDA
  • Extensive QC testing, including functionality, sterility, and endotoxin
  • Mycoplasma USP <63> testing is standard on all lots
  • Custom sizes and packaging available on request

† DMF filing pending.

Improved NK Cell Expansion in Chemically-defined Conditions


This product is shipped at 2-8°C with cold packs. Upon receipt, store immediately at 2-8°C and protect from light.
Shelf Life
Unopened liquid medium is stable for 18 months from date of manufacture, as indicated on the label, when stored at 2-8°C and protected from light. Once opened, the product should be stored at 2-8°C in the dark and used within 4 weeks.
Product Inserts
Product Sheets
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