Topic: Achieving High Productivities Through Bioreactor Optimization at Lower than Peak Cell Densities in a Perfusion Process
Presenter: Luis Rodriguez, PhD, R&D Manager, Bioproduction

Cell therapy developers focused on regenerative medicine rely on human mesenchymal stromal/stem cells (MSCs) for their ability to expand and differentiate across a variety of cell types. 

To generate high-quality MSCs in sufficient quantities for large-scale clinical trials, many cell therapy manufactures are moving from static to dynamic systems. MSC expansion in a closed sterile environment can help minimize risk of contamination, reduce production costs, and streamline the transition from research to clinical scale.

In this recorded presentation, we explore methods that ensure your perfusion process maximizes mAb production. Watch as we reveal the latest techniques for achieving high productivity in a continuous steady-state perfusion culture with BalanCD CHO Perfusion. Discover how optimizing bioreactor parameters and using the right cell culture medium can put you at the forefront of bioprocessing efficiency and innovation.

Key Learning Objectives:

• Learn how to use perfusion mimic models to assess a perfusion medium.
• Understand how to scale from a micro bioreactor to a table-top perfusion capable bioreactor.
• Master the optimization of the perfusion process to achieve increased productivity.