MassivEV EV Purification Column PS

Fujifilm Wako has developed the MassivEV EV Purification Column PS, which utilizes our proprietary EV isolation and purification technology known as the PS affinity method¹). Used in conjunction with the specialized MassivEV Purification Buffer Set (Catalog ID 295-96601), this system enables convenient isolation and purification of EVs, including exosomes, from liter-scale cell culture supernatants.

About commercial or for-profit purposes

Please use this product for research purposes only. If you wish to use it for commercial or for-profit purposes, please contact Fujifilm Wako at wkuslabchem@fujifilm.com.

for Genetic Research

• High-purity EVs can be efficiently isolated and purified from large volumes of cell culture supernatants (from 10 mL to several liters)
• Eliminates the need for expensive equipment like tangential flow filtration (TFF) systems. *Only a peristaltic pump is required.

Made by FUJIFILM Wako Pure Chemical Corporation and distributed by FUJIFILM Irvine Scientific.

• For research use or further manufacturing use only. Not for use in diagnostic procedures. 
• Product content may differ from the actual image due to minor specification changes etc. 
• If the revision of product standards and packaging standards has been made, there is a case where the actual product specifications and images are different. 

1. Nakai, W. et al.: Sci. Rep. 6(1), 1(2016).
   A novel affinity-based method for the isolation of highly purified extracellular vesicles
2. Mansouri, N. et al.: JCI insight, 4(21), e128060(2019).
   Mesenchymal stromal cell exosomes prevent and revert experimental pulmonary fibrosis through modulation of monocyte phenotypes
3. Angioni, R. et al.: Int. J. Mol. Sci., 21(22), 8874(2020).
   Administration of human MSC-derived extracellular vesicles for the treatment of primary sclerosing cholangitis: preclinical data in MDR2 knockout mice
4. Perets, N. et al.: Mol. Autism, 11(1), 65(2020).
   Exosomes derived from mesenchymal stem cells improved core symptoms of genetically modified mouse model of autism Shank3B
5. Théry, C. et al.: J. Extracell. Vesicles, 7(1), 1535750(2018).
   Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines