CTGF (Full+N-terminal region) ELISA Kit Wako

for Immunochemistry

Connective Tissue Growth Factor (CTGF) is a secreted protein of approximately 38 kDa produced by umbilical vein and vascular endothelial cells. It is involved in cell adhesion and the proliferation and differentiation of chondrocytes. It is also considered a key factor in tissue fibrosis and reported as a potential marker of fibrosis.

CTGF contains four domains, modules 1-4. The N-terminal region (modules 1 and 2) is known as a candidate biomarker of idiopathic pulmonary fibrosis (IPF)1). However, it has been difficult to accurately measure only the N-terminal region of CTGF, because the N-terminal region and platelet-derived full-length CTGF are both present in the blood.

Manufacturer:	FUJIFILM Wako Pure Chemical Corporation
GHS:	Danger

96 tests

 
Made by FUJIFILM Wako Pure Chemical Corporation and distributed by FUJIFILM Irvine Scientific 

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1. Kono, M. et al.: Clin. Chim. Acta, 412, 2211(2011).
   Plasma CCN2 (connective tissue growth factor; CTGF) is a potential biomarker in idiopathic pulmonary fibrosis (IPF)
2. Miyazaki, O. et al.: Ann. Clin. Biochem., 47, 205(2010).
   Subtraction method for determination of N-terminal connective tissue growth factor

• Kogiso, T. et al.: PLoS One, 19(1), e0296375(2024).
  Serum level of full-length connective tissue growth factor reflects liver fibrosis stage in patients with Fontan-associated liver disease
• Morishima, N. et al.: Pract. Lab. Med., 40, e00402(2024).
  Serum levels of the N-terminal fragment of connective tissue growth factor is a novel biomarker for chronic pancreatitis