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Anti P2RY12, Guinea Pig
In stock
Catalog ID
015-28871, 011-28873
Details
P2RY12 (also known as P2Y12) is an adenosine 5‘-diphosphate (ADP) receptor and a member of the P2Y family of purinergic G protein-coupled receptors. In the central nervous system, it is specifically expressed in microglia1 but not macrophages, and is used as a homeostatic microglial marker.
Anti P2RY12, Guinea Pig, is a guinea pig polyclonal antibody, raised against P2RY12. It can be used to perform multiplex immunohistochemistry.
Antibody Information
| Manufacturer: | FUJIFILM Wako Pure Chemical Corporation |
| Clonality: | Polyclonal |
| Antigen: | Synthetic peptide (P2RY12 C-terminal sequence) |
| Host: | Guinea pig |
| Formulation: | PBS, 0.05% Sodium azide |
| Conjugate: | Unconjugated |
| Cross-reactivity: | Mouse* |
| Application: | Immunohistochemistry (frozen section) 1:500-2,000 |
| Precautions for Use: | Avoid repeated freeze and thaw. |
| Appearance: | Liquid |
| Concentration: | Protein: 0.45 - 0.65 mg/mL |
| Alias: | Anti P2Y12, Guinea Pig |
*Experience with rats has been reported. For details, please see “Data”.
Made by FUJIFILM Wako Pure Chemical Corporation and distributed by FUJIFILM Irvine Scientific.
- For research use or further manufacturing use only. Not for use in diagnostic procedures.
References
- Butovsky, O. et al.: Neurosci., 17(1), 131(2014).
Identification of a unique TGF-β–dependent molecular and functional signature in microglia - Keren-Shaul, H. et al.: Cell, 169(7), 1276(2017).
A unique microglia type associated with restricting development of Alzheimer’s disease - Maeda, J. et al.: Brain Commun., 3(1), fcab011(2021).
Distinct microglial response against Alzheimer's amyloid and tau pathologies characterized by P2Y12 receptor
Specifications
Storage
Keep at -20°C
Product Inserts
Protocols
Data & Technical Information
Product Specifications
