Recombinant Human IGF-1 ACF

Catalog ID: 95119

95119 - Recombinant Human IGF-1 ACF
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Recombinant Human IGF-1 ACF
95119 - 20 µg Login above or Register for pricing

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Insulin-like growth factor 1 (IGF-1) is produced primarily by the liver as an endocrine hormone and in target tissues in a paracrine/autocrine fashion. IGF-1 activates the IGF-1 receptor (IGF1R) and the insulin receptor to stimulate systemic body growth and growth-promoting effects on almost every cell in the body, especially skeletal muscle, cartilage, bone, liver, kidney, nerve, skin, hematopoietic, and lung cells. IGF-1 is a potent activator of the AKT signaling pathway, which is known to be a stimulator of proliferation and an inhibitor of programmed cell death. The IGF-1 gene is located on chromosome 12. Mature human IGF-1 is 100% homologous with bovine and porcine proteins. Recombinant Human IGF-1 ACF is a non-glycosylated protein, containing 70 amino acids, with a molecular weight of 7.7 kDa (2-4).

  • Accession Number: P05019
     
  • Synonyms: Somatomedin C, mechano growth factor, IGF-1A
     
  • Purity: ≥96% determined by reducing and non-reducing SDS-PAGE analysis
     
  • Bioactivity: The ED50 is typically less than 5 ng/mL. ED50 is determined by the dose-dependent proliferation of FDC-P1 cells.
     
  • Animal component-free and carrier-free
     
  • Custom packaging available

For research or further manufacturing use only.

Also available in other sizes. Please contact us for details.

Contact us for international pricing.

Storage

Store at ≤ -10°C