Recombinant Human SCF ACF

Catalog ID: 95115

95115 - Recombinant Human SCF ACF
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Recombinant Human SCF ACF
95115 - 10 µg Login above or Register for pricing

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SCF is produced by fibroblasts and endothelial cells. SCF binds to and activates the receptor tyrosine kinase c-Kit. Activation of c-Kit receptor is thought to play a role in cell survival, migration and proliferation in different cell types. Additionally, SCF is critical for promoting proliferation, survival and differentiation of hematopoietic progenitor cells as well as melanocytes and germ cells. SCF/c-Kit signaling is also essential for embryonic hematopoiesis. Although murine and rat SCF are active on human cells, human SCF shows little or no activity on rat and murine cells. Recombinant Human SCF is a non-glycosylated protein, containing 165 amino acids, with a molecular weight of 18.4 kDa.

  • Accession Number: P21583
     
  • Synonyms: c-Kit Ligand, KL, Steel Factor, MGF
     
  • Purity: ≥ 95% purity. Determined by HPLC, reducing and non-reducing SDS-PAGE, and UV spectroscopy
     
  • Bioactivity: ED50 typically less than 10 ng/mL. ED50 determined by dose-dependent proliferation of human TF1 cells.
     
  • Animal component-free and carrier-free
     
  • Custom packaging available

For research or further manufacturing use only.

Also available in other sizes. Please contact us for details.

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Storage

Store at ≤ -10°C