Cytogenetics Media

CHANG Medium® is the gold standard for cytogenetics applications. CHANG Amnio®, CHANG Medium® In Situ, CHANG Medium C®, and CHANG Medium D® are specially optimized for culturing human amniotic fluid cells and Chorionic Villus Sampling (CVS) during prenatal care. CHANG Marrow®, CHANG Medium BMC®, and CHANG Medium MF® are specially optimized for culturing bone marrow and peripheral blood during postnatal care.

CHANG Amnio® is a complete, ready-to-use medium with an antibiotic developed for the culture of human amniotic fluid cells, Chorionic Villus Sampling (CVS), and tissues for use in karyotyping and other antenatal testing. With an improved blend of basal media and serum, Irvine Scientific’s Chang Amnio® has been shown to yield higher growth than other commercially available media.


Chang Medium® C was developed for the primary culture of human amniotic fluid cells for use in karyotyping and other antenatal genetic testing. This formula has been optimized for both open and closed systems and consists of a two part system: a liquid basal medium and supplement (frozen or lyophilized).


Chang Medium® D was developed for the primary culture of human amniotic fluid cells for use in karyotyping and other antenatal genetic testing. This formula has been optimized for both flask and in situ methodologies. Packaged in single bottles, ready-to-use with no mixing required. For in vitro diagnostic use.


Chang Medium® In Situ was developed for the primary culture of human amniotic fluid cells for use in karyotyping and other antenatal genetic testing. This formula has been optimized for in situ methodologies. Packaged in single bottles, ready-to-use with no mixing required. For in vitro diagnostic use.


CHANG Marrow® is a complete, ready-to-use medium optimized to support bone marrow cultures for karyotyping and other genetic testing of various hematological disorders. After an extensive optimization process to create a superior, innovative blend of growth factors, Irvine Scientific’s CHANG Marrow® has been shown to out-perform other commercially available media in clinical studies. Packaged in single bottles, ready-to-use with no mixing required. For in vitro diagnostic use.


CHANG Medium® BMC is intended for use in the primary culture of clinical human bone marrow culture for karyotyping and other genetic testing of various hematological disorders.


CHANG Medium® MF is intended for the use in culturing human peripheral blood cells, bone, marrow, T-cell lymphocytes, and other human specimens for purposes of cytogenetic analysis.


Minimum Essential Medium (MEM) was developed by Harry Eagle, and is one of the most widely used of all synthetic cell culture media. It is designed for a wide range of species and cells.


Cell culture reagents are solutions designed to produce a chemical reaction to detect, measure, or produce other substances, thereby optimizing results.


In cell culture, enzymes can be used to isolate individual cells or to start primary cultures, and also to detach adherent cells from the culture surface to passage the cells.