Media and Products

We provide a full range of high quality products and services that are sure to help you improve your results and simplify your processes.

Selecting, sustaining, and storing the most viable sperm is essential for optimal sperm preparation. The ideal sperm preparation medium helps maintain a stable pH and osmolality while providing the proper physiological environment for survival.

Irvine Scientific has been at the forefront of developing andrology media since 1987. Isolate® was one of the first FDA-cleared density gradient sperm separation medium and has been cited in hundreds of articles. Freezing Medium TYB is a unique egg-yolk based product that remains the standard for performance in sperm cryopreservation. Refrigeration Medium TYB is the only FDA-cleared and CE marked medium for sperm stored at refrigerated temperatures without glycerol. Multipurpose Handling Medium®, is the first medium containing both HEPES and MOPS to provide a secure and stable environment for handling sperm and oocytes.

Irvine Scientific provides the highest quality products for optimal sperm preparation for IUI, IVF, ICSI, or any other ART process.


Micromanipulation of eggs and sperm requires specialized media, solutions, equipment and training. Irvine Scientific offers high quality media designed to facilitate the in vitro preparation of gametes prior to micromanipulation procedures, such as Intra-Cytoplasmic Sperm Injection (ICSI), assisted hatching, and embryo biopsy.

ICSI has grown to be the most common ART procedure in many parts of the world due to its higher rate of fertilization and ability to fertilize with low quality sperm samples. Hyaluronidase and polyvinylpyrrolidone (PVP) are the two essential ICSI solutions. Hyaluronidase prepares the oocytes by removing the cumulus surrounding it, and PVP slows or immobilizes sperm to facilitate selection of motile sperm for injection. Multipurpose Handling Media provides a safe environment for fertilization before transfer into embryo culture medium.

Embryo biopsy is a rapidly growing technique due to increased demand for preimplantation genetic diagnosis (PGD). A portion of the embryo or blastocyst is biopsied and tested for genetic disorders prior to embryo transfer. The results aid selection of genetically normal embryos and, in some cases, may also help pregnancy rates. Embryo Biopsy Medium is a culture medium for 4-10 cell embryos during biopsy for PGD.

Assisted hatching facilitates the embryo's hatching process from the zona pellucida. The zona is drilled using a PZD needle, laser pulsing, or Acidified Tyrode's Solution.  Tyrode's Solution - Acidified is a micromanipulation media with very acidic pH that can break down the zona pellucida.


Natural and recombinant macromolecules when added to embryo culture medium can influence viability as demonstrated in an increase in pregnancy outcomes.


This is a sterile mineral oil providing a barrier overlay to ensure minimal evaporation of media, maintain osmolality and minimize pH drift.


Produced from an advanced, state-of-the-art Water For Injection (WFI) system, Irvine Scientific’s WFI Quality Water is the most suitable. WFI Quality Water meets and exceeds both USP and EP specifications.


The world leader in reproduction biotechnology, Cryo Bio System provides expertise for the cryopreservation of biological samples to scientists and embryologists through their range of high security products.


Needles with an optimized design that improves patient comfort while maximizing aspiration efficiency and success.


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Successful embryo cryopreservation is an important step for IVF laboratories to maximize a patient's IVF cycle. Irvine Scientific provides cryopreservation media for conventional slow-freezing and thawing of cleavage and blastocyst stage embryos.


Our preservation media for human sperm produces the maximum survival of sperm, including yolk-based TYB for freezing or refrigeration, which is only offered by Irvine Scientific.